Wenlong Sheng
2020-09-25
Affiliation：
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences)
Contact details
Telephone
+86 15618694162
shengwenlong1121@163.com
Address
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), 28789 Jingshidong Road, Licheng District, Ji’nan 250103, Shandong Province, PR China
Biography
Wenlong Sheng，majoring in neurobiology, received the Ph.D. in Fudan University in 2016, and he is a research associate of Biology Institute of Shandong Academy of Sciences. Wenlong Sheng attended a short-term study at Tohoku University in Japan in 2015. He visited National Academy of Sciences of Georgia in 2018.
Research
Wenlong Sheng’s research interests include the functional assessment using cell and zebrafish models, and the study of neuromodulation of neurotransmitters.
Funding (year, title, source, amount, role)
1. The expression of melatonin receptors in zabrafish retina and the modulatory of melatonin on the response of ipRGC. Department of Science and Technology of Shandong Province. PI. 50,000 Yuan RMB. 2018.03-2020.06.
2. Special project of A-class talents of Shandong Academy of Sciences. Shandong Academy of Sciences. PI, 300,000 Yuan RMB, 2018.01-2020.12.
3. Cellular localization of melatonin receptors in zebrafish and pigeon retina. Shandong Academy of Sciences. PI, 200,000 Yuan RMB, 2019.01-2020.12.
4. Science and Technology Development Fund Project of Shandong Academy of Sciences. Shandong Academy of Sciences. PI, 30,000 Yuan RMB, 2019.01-2019.12.
5. Research Fund for doctoral students. Fudan University. PI, 30,000 Yuan RMB, 2014.09-2016.06.
Publications
1. PanJia, DongmeiLiu， ZihanZhuang, LeyangQu,CaiyunLiu, YongfangZhang, ZiluLi, HanchuangZhu, YaminYu, XueZhang, Wenlong Sheng, BaocunZhu. A highly selective ratiometric fluorescence probe for bioimaging of hypobromous acid in living cells and zebrafish. Sensors & Actuators: B. Chemical. 320 (2020) 128583. （IF=7.100, co- corresponding author）
2. Xiwei Li, Qingxia Duan, Yamin Yu, Kun Wang, Hanchuang Zhu, Xue Zhang, Caiyun Liu, Pan Jia, Zilu Li, Wenlong Sheng, Baocun Zhu. A coumarin-based fluorescent probe for Hg2+ and its application in living cells and zebrafish. Luminescence. 2020;1–6.（IF=1.855, co- corresponding author）
3. Hanchuang Zhu, Caiyun Liu, Changxu Liang, Bin Tian, Hanming Zhang, Xue Zhang, Wenlong Sheng, Yamin Yu, Shengyun Huang, Baocun Zhu. A new phenylsulfonamide-based Golgi-targeting fluorescent probe for H2S and its bioimaging applications in living cells and zebrafish. Chemical Communications. 2020, 56, 4086-4089.（IF=5.996, co- corresponding author）
4. Kun Wang, Pan Jia, Xiwei Li, Xue Zhang, Caiyun Liu, Yamin Yu, Hanchuang Zhu, Zilu Li, Wenlong Sheng, Baocun Zhu. A simple p-methylaminophenylether-based fluorescent probe for detecting native hypochlorous acid in live cells and zebrafish. Dyes and Pigments. 177 (2020) 108310. （IF=4.631, co- corresponding author）
5. Yamin Yu, Caiyun Liu, Bin Tian, Xinyu Cai, Hanchuang Zhu, Pan Jia, Zilu Li, Xue Zhang, Wenlong Sheng, Baocun Zhu. A novel highly selective ratiometric fluorescent probe with large emission shift for detecting mercury ions in living cells and zebrafish. Dyes and Pigments. 177 (2020) 108290. （IF=4.631, co- corresponding author）
6. Zhu Hanchuang, Liu Caiyun, Zhang Hanming, Jia Pan, Li Zilu, Zhang Xue, Yu Yamin, Sheng Wenlong, Zhu Baocun. A Simple Long-wavelength Fluorescent Probe for Simultaneous Discrimination of Cysteine/Homocysteine and Glutathione/Hydrogen Sulfide with Two Separated Fluorescence Emission Channels by Single Wavelength Excitation. Anal Sci. 2020 Feb 10;36(2):255-262. （IF=2.049, co- corresponding author）
7. Xue Zhang, Caiyun Liu, Xinyu Cai, Bin Tian, Hanchuang Zhu, Yanan Chen, Wenlong Sheng, Pan Jia, Zilu Li, Yamin Yu, Shengyun Huang ,Baocun Zhua. A highly specific Golgi-targetable fluorescent probe for tracking cysteine generation during the Golgi stress response. Sensors & Actuators: B. Chemical 310 (2020) 127820. （IF=7.100, co- corresponding author）
8. Xue Zhang, Caiyun Liu, Yanan Chen, Xinyu Cai, Wenlong Sheng, Hanchuang Zhu, Pan Jia, Zilu Li, Shengyun Huang, Baocun Zhu. Visualization of cysteine level during Golgi stress with a novel targeting highly specific fluorescent probe. Chemical Communications. 2020, 56, 1807-1810（IF=5.996, co- corresponding author）
9. Hanchuang Zhu, Changxu Liang, Xinyu Cai, Hanming Zhang, Caiyun Liu, Pan Jia, Zilu Li, Yamin Yu, Xue Zhang, Wenlong Sheng, Baocun Zhu. Rational Design of a Targetable Fluorescent Probe for Visualizing H2S Production under Golgi Stress Response Elicited by Monensin. Anal. Chem. 2020, 92, 1883−1889.（IF=6.785, co- corresponding author）
10. Zilu Li, Chen Yu, Yanan Chen, Zihan Zhuang, Bin Tian, Caiyun Liua, Pan Jia, Hanchuang Zhu, Yamin Yu, Xue Zhang, Wenlong Sheng, Baocun Zhu. A novel Pd2+-free highly selective and ultrasensitive fluorescent probe for detecting CO-releasing molecule-2 in live cells and zebrafish. Dyes and Pigments 174 (2020) 108040. （IF=4.631, co- corresponding author）
11. Xue Zhang, Yanan Chen, Xinyu Cai, Caiyun Liu, Pan Jia, Zilu Li, Hanchuang Zhu, Yamin Yu, Kun Wang, Xiwei Li, Wenlong Sheng, Baocun Zhu. A highly sensitive rapid-response fluorescent probe for specifically tracking endogenous labile Fe2+ living cells and zebrafish. Dyes and Pigments 174 (2020) 108065. （IF=4.631, co- corresponding author）
12. Pan Jia, Zihan Zhuang, Caiyun Liua, Zuokai Wang, Qingxia Duan, Zilu Li, Hanchuang Zhu, Fenfen Zhang, Wenlong Sheng, Baocun Zhu. Development of a ratiometric fluorescent probe with a large emission shift for imaging ONOO- in live cells and zebrafish. Dyes and Pigments 173 (2020) 107942. （IF=4.631, co- corresponding author）
13. Pan Jia, Zihan Zhuang, Dongmei Liu, Yanan Chen, Bin Tian, Caiyun Liua, Zilu Li, Hanchuang Zhu, Yamin Yu, Xue Zhang, Wenlong Sheng, Shengyun Huang, Baocun Zhu. A novel highly selective fluorescent probe for imaging endogenous hypobromous acid in living cells and zebrafish. Sensors & Actuators: B. Chemical 305 (2020) 127460. （IF=7.100, co- corresponding author）
14. Wenlong Sheng, Meng Jin, Ge Pan, Shijun Weng, Attila Sik, Liwen Han, Kechun Liu. Cellular localization of melatonin receptor Mel1b in pigeon retina. Neuropeptides 78 (2019) 101974. （IF=2.411, first anthor, co- corresponding author）
15. Qingxia Duan, Pan Jia, Zihan Zhuang, Caiyun Liu, Xue Zhang, Zuokai Wang, Wenlong Sheng, Zilu Li, Hanchuang Zhu, Baocun Zhu, and Xiaoling Zhang. Rational design of a hepatoma-specific fluorescent probe for HOCl and its bioimaging applications in living HepG2 cells. Anal. Chem., 2019, 91, 2163−2168.（IF=6.785, co- corresponding author）
16. Qingxia Duan, Hanchuang Zhu, Caiyun Liu, Ruifang Yuan, Zhaotong Fang, Zuokai Wang, Pan Jia, Zilu Li, Wenlong Sheng and Baocun Zhu. A carbonothioate-based far-red fluorescent probe for the specific detection of mercury ions in living cells and zebrafish. Analyst, 2019, 144, 1426–1432.（IF=3.978, co- corresponding author）
17. Qingxia Duan, Xiaoyu Lv, Caiyun Liu, Zhuofan Geng, Fenfen Zhang, Wenlong Sheng, Zuokai Wang, Pan Jia, Zilu Li, Hanchuang Zhu, and Baocun Zhu. Dichlororesorufin-Based Colorimetric and Fluorescent Probe for Ultrasensitive Detection of Mercury Ions in Living Cells and Zebrafish. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2019, 58, 11−17.（IF=3.573, co- corresponding author）
18. Zuokai Wang, Caiyun Liu, Xin Wang, Qingxia Duan, Pan Jia, Hanchuang Zhu, Zilu Li, Xue Zhang, Xiaohua Ren, Baocun Zhu, Wenlong Sheng. A metal-free near-infrared fluorescent probe for tracking the glucose-induced fluctuations of carbon monoxide in living cells and zebrafish. Sensors & Actuators: B. Chemical 291 (2019) 329–336. （IF=7.100, co- corresponding author）
19. Zuokai Wang, Ziyang Zhao, Caiyun Liu, Zhuofan Geng, Qingxia Duan, Pan Jia, Zilu Li, Hanchuang Zhu, Baocun Zhu, Wenlong Sheng. A long-wavelength ultrasensitive colorimetric fluorescent probe for carbon monoxide detection in living cells. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2019, 18, 1851–1857. （IF=2.831, co- corresponding author）
20. Pan Jia, Zihan Zhuang, Caiyun Liu, Zuokai Wang, Qingxia Duan, Zilu Li, Hanchuang Zhu, Bin Du, Baocun Zhu, Wenlong Sheng, Baotao Kang. A highly specific and ultrasensitive p-aminophenylether-based fluorescent probe for imaging native HOCl in live cells and zebrafish. Analytica Chimica Acta, 2019, 1052, 131-136. （IF=5.977, co- corresponding author）
21. Pan Jia, Dongmei Liu, Zihan Zhuang, Caiyun Liu, Zilu Li, Chen Yu, Yanan Chen, Hanchuang Zhu, Xue Zhang, Yamin Yu, Baocun Zhu, Wenlong Sheng. Dicyanoisophorone-Derived Near-Infrared Fluorescent Probe for Ultrasensitive Detection of Peroxynitrite in Living Cells and Zebrafish. INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH. 2019, 58, 19778−19784. （IF=3.573, co- corresponding author）
22. Shan-shan Liu, Wen-long Sheng, Yun Li, Shan-shan Zhang, Jing-jing Zhu, Hui-min Gao, Li-hua Yan, Zhi-min Wang, Lu Gao, Mei Zhang. Chemical constituents from Alismatis Rhizoma and their anti-inflammatory activities in vitro and in vivo. Bioorganic Chemistry 92 (2019) 103226. （IF=4.831, co-first author）
23. Caiyun Liu, Qingxia Duan, Xue Zhang, Zilu Li, Pan Jia, Hanchuang Zhu, Yamin Yu, Zuokai Wang, Baocun Zhu, Wenlong Sheng. A novel hepatoma-specific fluorescent probe for imaging endogenous peroxynitrite in live HepG2 cells. Sensors & Actuators: B. Chemical 289 (2019) 124–130. （IF=7.100, co- corresponding author）
24. Caiyun Liu, Pan Jia, Zihan Zhuang, Zuokai Wang, Qingxia Duan, Zilu Li, Hanchuang Zhu, Xue Zhang, Baocun Zhu, Wenlong Sheng. A water-soluble and highly specific fluorescent probe with large stokes shift for imaging basal HOCl in living cells and zebrafish. Sensors & Actuators: B. Chemical. 291 (2019) 243–249. （IF=7.100, co- corresponding author）
25. Caiyun Liu, Xue Zhang, Zilu Li, Yanan Chen, Zihan Zhuang, Pan Jia, Hanchuang Zhu, Yamin Yu, Baocun Zhu, Wenlong Sheng. Novel Dimethylhydrazine-Derived Spirolactam Fluorescent Chemodosimeter for Tracing Basal Peroxynitrite in Live Cells and Zebrafish. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2019, 67, 6407−6413. （IF=4.192, co- corresponding author）
26. Caiyun Liu, Zilu Li, Chen Yu, Yanan Chen, Dongmei Liu, Zihan Zhuang, Pan Jia, Hanchuang Zhu, Xue Zhang, Yamin Yu, Baocun Zhu, Wenlong Sheng. Development of a concise rhodamine-formylhydrazine type fluorescent probe for highly specific and ultrasensitive tracing of basal HOCl in live cells and zebrafish. ACS Sens. 2019 4(8):2156-2163. （IF=7.333, co- corresponding author）
27. Zilu Li, Caiyun Liu, Chen Yu, Yanan Chen, Pan Jia, Hanchuang Zhu,Xue Zhang, Yamin Yu, Baocun Zhu and Wenlong Sheng. A highly selective and sensitive red-emitting fluorescent probe for visualization of endogenous peroxynitrite in living cells and zebrafish. Analyst. 2019, 144, 3442–3449. （IF=3.978, co- corresponding author）
28. Zilu Li, Caiyun Liu, Chen Yu, Ruifang Yuan, Pan Jia, Zuokai Wang, Qingxia Duan, Hanchuang Zhu, Baocun Zhu, Wenlong Sheng. A water-soluble and highly specific fluorescent probe for imaging thiophenols in living cells and zebrafish. NEW JOURNAL OF CHEMISTRY., 2019, 43, 6746—6752. （IF=3.288, co- corresponding author）
29. Zilu Li, Chen Yu, Yanan Chen, Zihan Zhuang, Bin Tian, Caiyun Liu, Pan Jia, Hanchuang Zhu, Wenlong Sheng, Baocun Zhu. A novel water-soluble fluorescent probe with ultra-sensitivity over a wider pH range and its application for differentiating cancer cells from normal cells. Analyst, 2019, 144, 6975. （IF=3.978, co- corresponding author）
30. Zilu Li, Chen Yu, Yanan Chen, Caiyun Liu, Pan Jia, Hanchuang Zhu, Xue Zhang, Wenlong Sheng, Baocun Zhu. A novel ratiometric fluorescent probe for highly sensitive and selective detection of peroxynitrite and its application for tracing endogenous peroxynitrite in live cells. Analytical Methods, 2019, 11, 5699. （IF=2.596, co- corresponding author）
31. Hanchuang Zhu, Caiyun Liu, Ruifang Yuan, Ruikang Wang, Hanming Zhang, Zilu Li, Pan Jia, Baocun Zhu, Wenlong Sheng. A simple highly specific fluorescent probe for simultaneous discrimination of cysteine/homocysteine and glutathione/hydrogen sulfide in living cells and zebrafish using two separated fluorescence channels under single wavelength excitation. Analyst, 2019, 144, 4258–4265. （IF=3.978, co- corresponding author）
32. Hanchuang Zhu, Hanming Zhang, Changxu Liang, Caiyun Liu, Pan Jia, Zilu Li, Yamin Yu, Xue Zhang, Baocun Zhu, Wenlong Sheng. A novel highly sensitive fluorescent probe for bioimaging biothiols and its applications in distinguishing cancer cells from normal cells. Analyst, 2019, 144, 7010. （IF=3.978, co- corresponding author）
33. Xue Zhang, Yanan Chen, Caiyun Liu, Zihan Zhuang, Zilu Li, Pan Jia, Hanchuang Zhu, Yamin Yu, Baocun Zhu, Wenlong Sheng. A novel hexahydropyridazin-modified rhodamine fluorescent probe for tracing endogenous/exogenous peroxynitrite in live cells and zebrafish. Dyes and Pigments 170 (2019) 107573. （IF=4.631, co- corresponding author）
34. Liwen Han, Wenlong Sheng, Xiaobin Li, Attila Sik, Houwen Lin, Kechun Liu, Lizhen Wang. Novel carbohydrate modified berberine derivatives: synthesis and in vitro anti-diabetic investigation. Med. Chem. Commun., 2019, 10, 598. （IF=2.807, co-first author）
35. Sheng Wenlong, Chen Weiyi, Yang Xiongli, Zhong Yongmei, Weng Shijun. Co-expression of two subtypes of melatonin receptor on rat M1-type intrinsically photosensitive retinal ganglion cells. PLoS One (2015) 10:e0117967. （IF=2.740, first author）
36. Two novel non-holostane type glycosides from the viscera of sea cucumber Apostichopus japonicas. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 2019.1576643. （IF=1.170，3/8）
37. TWO NOVEL HOLOSTANE-TYPE GLYCOSIDES FROM THE VISCERA OF SEA CUCUMBER APOSTICHOPUS JAPONICUS WITH ANTITUMOR ACTIVITIES. Rev. Roum. Chim., 2019, 64(4), 353-359. （IF=0.395，3/8）
38.Activation of BDNF-TrkB signaling pathway-regulated brain inflammation in pentylenetetrazole-induced seizures in zebrafish. Fish and Shellfish Immunology 83 (2018) 26–36. （IF=3.298，2/6）
39. Synergistic effects of Pb and repeated heat pulse on developmental neurotoxicity in zebrafish. Ecotoxicology and Environmental Safety 172 (2019) 460–470. （IF=4.527， 4/6）
40. A highly specific and sensitive ratiometric fluorescent probe for carbon monoxide and its bioimaging applications. New J.Chem., 2018, 42, 14417. （IF=3.069，4/8）
41. Temporal Neuromodulation of Retinal Ganglion Cells by Low-Frequency Focused Ultrasound Stimulation. IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, (2018) 26 (5). （IF=3.478， 4/12）
42. RdgB2 is required for dim-light input into intrinsically photosensitive retinal ganglion cells. MBoC (2015) 26 3671-3678. （IF=3.905， 5/9）
43. Signalling mechanism for somatostatin receptor 5-mediated suppression of AMPA responses in rat retinal ganglion cells. Neuropharmacology 107 (2016) 215e226. （IF=4.367， 2/6）
44. Orexin-A differentially modulates AMPA-preferring responses of ganglion cells and amacrine cells in rat retina. Neuropharmacology 93 (2015) 80-93. （IF=4.367， 6/9）
45. Effects of streptozotocin on pancreatic islet β-cell apoptosis and glucose metabolism in zebrafish larvae. 2020, Fish Physiol Biochem. （4/8）
Patents
1. Method for preparing high-purity marine polyunsaturated fatty acid phospholipid from cod viscera, China patent ZL2016111466659.
Awards and other activities
1. 2016, Introduced talents, Shandong Academy of Sciences.
2. Reviewers of journal paper: Analytical Chemistry.
