Chen Sun
2020-09-25
Affiliation：
Biology Institute of Qilu University of Technology (Shandong Academy of Sciences)
Contact details
Telephone
Email
Address
Biology Institute
Qilu University of Technology (Shandong Academy of Sciences)
28789 Jingshidong Road, Licheng District,
Jinan 250103,
Shandong Province,
PR China.
Biography
Chen Sun received a PhD from the School of Life Sciences, Shandong University in the field of Cell Biology in 2014. She later worked in the Biology Institute of Qilu University of Technology (Shandong Academy of Sciences). At present, she is an assistant researcher and mainly engaged in the construction of human disease models based on zebrafish and the research of ototoxicity.
Research
Dr Chen Sun construct a transgenic zebrafish model based on the promoter of N-acetylated alpha-linked acidic dipeptidase 2 gene and investigates the possibility that active peptides from marine food resources prevent drug-induced hearing loss.
Funding (year, title, source, amount, role)
1. 2015, The Study on the Function of Ptena and Ptenb Genes in Zebrafish Inner Ear Hair Cells, Shandong Provincial Natural Science Foundation, 50,000, Leader.
2. 2015, Establishment of Zebrafish Tumor Model Based on PTEN Gene Knockout, Shandong Academy of Sciences, 100,000, Leader.
Publications
1. A novel active peptide from Rapana venosa protects against gentamicin-induced sensory hair cell loss in zebrafish, 2020, International Journal of Peptide Research and Therapeutics.
2. A new active peptide from Neptunea arthritica cumingii exerts protective effects against gentamicin-induced sensory-hair cell injury in zebrafish, 2019, Drug and Chemical Toxicology.
3. Tenacissoside H exerts an anti-inflammatory effect by regulating the nf-κb and p38 pathways in zebrafish, 2018, Fish & Shellfish Immunology.
4. A rapid assessment for predicting drug-induced hepatotoxicity using zebrafish, 2016, Journal of Pharmacological and Toxicological Methods.
5. PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice, 2014, NeuroReport.
Patents
1. A method for screening active compounds with regulating zebrafish gastrointestinal motility, 2019, ZL201610285698.5.
2. A special device for tumor transplantation of zebrafish juvenile fish, 2019, ZL201820864996.4
3. A method for marking zebrafish gastrointestinal tract with calcein, 2018, ZL201610286065.6.
