Professor  Serhiy V. KOMISARENKO (short CV)  

 

Surname: Komisarenko, first name: Serhiy. Citizenship:  Ukrainian, Sex – male.

Born: July 9th, 1943. Married, has one daughter. Passport: DU001448. Valid till 24/11/2021.

Home address – 19/21-15, Antonovicha Street, Kyiv-4, 01004, Ukraine Office address – 9 Leontovicha Street, Kyiv-30, 01030, Ukraine. 

Tel: +38044-2345974, +38050-3306488, fax: +38044-2796365, e-mail: svk@biochem.kiev.ua

 

Current occupations:

- Academician-Secretary of the National Academy of Sciences of Ukraine (from 2004-). Address: 54 Volodymyrska Street, Kyiv-30, 016001, Ukraine (full time)

- Director, Palladin Institute of Biochemistry (1989-1992 and from 1998-) (full time)

- Head, Department of Molecular Immunology, Palladin Institute of Biochemistry (1982-1992, from 1998-) (patr time)

- Chairman, Commission on Biosafety and Biosecurity at the National Security and Defence Council of    Ukraine (from 2007-);

- President, Ukrainian Biochemical Society (from 1999-)

- President, Ukrainian Biosafety Association (from 2013-)

 

Former occupations: 

- Ambassador of Ukraine to the United Kingdom (1992-1998)

- Deputy Prime Minister of Ukraine (1990-1992);

- Head, Laboratory of Immunochemistry (1975-1982). Palladin Institute of Biochemistry;

- Scientific Secretary of the Palladin Institute of Biochemistry (1972-1974); 

- Junior, Senior researcher in the Palladin Institute of Biochemistry (1969-1975)

 

Education: 

-Kyiv Medical Institute with distinction – MD (1960-1966); 

-Department of Mechanics & Mathematics of Kyiv State University (1964-1966); 

-Post graduate course in Biochemistry in the Institute of Biochemistry Kyiv – PhD (1966-1969); 

-Courses on Advanced Immunology in Pasteur Institute in Paris, France (1974-1975)

-Institute of Molecular Biology and Genetics in KYIV – DSci. in Molecular Biology and Biochemistry (1989)

 

Invited lecturer: 

- Kyiv National University: Head, Department of Biotechnology (2002-);  

- Kyiv Branch of Moscow Physico-Technical. Institute: Molecular Immunology (1982-1990);

- Kyiv State University: Course on Immunochemistry (1976-1984);

 

Degrees, titles and honours: 

Doctor of Medicine (1966), PhD in  Biochemistry (1970), Doctor of Sciences in Molecular Biology and Biochemistry (1989), Ukrainian State Award on Science (1979), Professor of Biochemistry (1989), Member (academician) of the Ukrainian Natl Acad.Sciences (1991) and of the Ukrainian Natl.Acad.Med.Sciences (1993), Honorary Doctor of Sciences: Kingston University, UK (1997) and North London University, UK (1997), Palladin Award in Biochemistry (2003), Mechnikov Award in Immunology (2011), Honorary Professor of Odesa National University (2010), Honorary Member of the Polish Biochemical Society (2011). 

Ambassador Extraordinary and Plenipotentiary of Ukraine (1992). 

Ukrainian State Awards: “Order of Freedom” (2018), Order of "Yaroslav the Wise" (2005), State Order of "Merit" (III degree-1996, II degree-1998, I degree-2013). PRChina: Order “Friendship”

 

Miscellaneous:  

1974-1975 – scholarship, Pasteur Institute in Paris, France; 1981 – scholarship, Sloan Kettering Cancer Institute, NY, USA.

Chairman, International Foundation of the National Memory of Ukraine (since 2009-),

President, Special Olympics Ukraine (since 2002-). 

Editor-in-chief:

"Ukrainian Biochemical Journal" (1989-1992 and since 1998-) and “Acta Biotechnologia” (since 2008-). 

Member of the Board: 

International Genomic Conference, BGI-China, in Shen Zhen, China (since 2017-)

International Journal “Europa”, Poland (since 1998-)

 

Some selected scientific publications (articles):

- Gergalova G., Lykhmus O., Komisarenko S., Skok M. α7 Nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways // Int J Biochem Cell Biol. – 2014 – V. 49. – P. 26-31.

- Kalashnyk O.M., et al., Komisarenko S.V. and Skok M.V. α7 nAChR-specific antibodies stimulate pro-inflammatory reaction in human astrocytes through p38-dependent pathway // Int Immunopharmacol. – 2014. – Sep 30. – pii: S1567-5769(14)00374-9.

- Chernyshenko V, et al., Komisarenko S. Fibrin(ogen)olytic and platelet modulating activity of a novel protease from the Echis multisquamatis snake venom // Biochimie. 2014 Jul 18. pii: S0300-9084(14)00168-0. doi: 10.1016/j.biochi.2014.06.015. 

- Lykhmus О, et al., Komisarenko S and Skok M. α7 Nicotinic Acetylcholine Receptor-Specific Antibody Induces Inflammation And Amyloid β42 Accumulation In The Mouse Brain To Impair Memory.  // PLoS ONE. 2015 May 27;10(3):e0122706. doi: 10.1371/journal.pone.0122706.

- Korotkevych N, et al.,.Komisarenko S. // PLoS ONE. 2015 May 27; doi: 10.1371/journal.pone.0127887.  

- Lykhmus O, et al., Komisarenko S, Skok M. The role of carbohydrate component of recombinant α7 nicotinic acetylcholine receptor extracellular domain in its immunogenicity and functional effects of resulting antibodies. // Immunobiology. 2016 Dec;221(12):1355-1361, doi: 10.1016/j.imbio.2016.07.012.

- Uspenska K., Lykhmus O., Gergalova G., Chernyshov V., Arias H.R., Komisarenko S., Skok M. Nicotine facilitates nicotinic acetylcholine receptor targeting to mitochondria but makes them less susceptible to selective ligands // Neurosci. Lett. – 2017. N 656. – P. 43-50.

- Lykhmus O., Uspenska K., Koval L., Lytovchenko D., Voytenko L., Horid'ko T., Kosiakova H., Gula N., Komisarenko S., Skok M. N-stearoylethanolamine protects the brain and improves memory of mice treated with lipopolysaccharide or immunized with the extracellular domain of 7 nicotinic acetylcholine receptor // Int. Immunopharmacol. – 2017. N 52. – P. 290-296.

- Nixdorff, K., Borisova, T., Komisarenko, S., Dando, M. Dual-use nano-neurotechnology: An assessment of the implications of trends in science and technology. Politics and the Life Sciences- Cambridge University Press,  37 (2), 180-202 (2018).

- Uspenska K., Lykhmus O., Arias H.R., Pons S., Maskos U., Komisarenko S., Skok M. Positive allosteric modulators of α7* or β2* nicotinic acetylcholine receptors trigger different kinase pathways in mitochondria // Int J Biochem Cell Biol. - 2018. N 99. - P. 226-235. 

- Uspenska K., Lykhmus O., Obolenskaya M., Pons S., Maskos U., Komisarenko S., Skok M. Mitochondrial nicotinic acetylcholine receptors support liver cells viability after partial hepatectomy // Front Pharmacol. - 2018. N 9. - P. 626.

 

Grants:

Numerous Ukrainian grants 

British Grant P633 (2014-2017): “Biosafety Education and Awareness Raising in Ukraine”;

STCU Grant (2018-2019): “The Biosafety Training Center for professionals involved in biological research”

European – OSCE grant (2018): (Biosafety Legislation in Ukraine”;

European Commission grant 823922 (2019-2022): “Theoretical and computational investigation of tuberculosis antimicrobial resistance development based on extensive experimental library of mycobacterium strains”.