Ning Li
2020-09-25
Affiliation：
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Engineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province
Contact details
Telephone
+86 13395310523
lining@sdas.org
Address
Biology Institute
Qilu University of Technology (Shandong Academy of Sciences)
28789 East Jingshi Road, Jinan
Shandong
P.R. China
Biography
Ning Li received her PHD in Fishery Resource field from Ocean University of China, Qingdao, China in 2014. She later worked in Shandong Freshwater Fisheries Research Institute, Jinan, China. Since 2018, She worked as an assistant professor in Biology Institute, Shandong Academy of Sciences, Jinan, China.
She learned the electrophysiological detection technique of larval and adult zebrafish from the professor Attila Sik from University of Birmingham, England. Her main interest is in the cardiotoxicity detection of human pharmaceuticals and the protective potential investigation of bioactive compounds derived from marine organisms.
Research
Using the zebrafish model, Ning Li investigates the toxic effect of microplastics and ZnO nanorods on nervous system and unravel the underlying mechanisms. She also analyzed the function and mechanism of action of candidate pathogenic genes from patients with sick sinus syndrome. Besides, She investigated mesenchymal stem cells from placenta.
Funding
1) 2019-2020, Construction of a site-mutation model of the candidate pathogenic gene ABCC9 and analysis of its electrophysiological function, the Youth Foundation Program of Shandong Academy of Sciences, ¥100,000, Project principal.
2) 2019-2020, The biotoxic effect and underlying mechanism of microplastics in water and sediment samples from the Yangtze Estuary, the Young Scientist Partnership Project between Shenyang Branch of Chinese Academy of Sciences and Shandong Academy of Sciences, ¥30,000, Project principal.
3) 2017 -2018, Population genetics analysis of wild and cultured populations of Culter alburnus, Open Fund for key Laboratory of Utilization and Breeding of Tropical and Subtropical Aquatic Resources of the Department of Agriculture, ¥20,000, Project principal.
4) 2014-2015, Study on the population genetic structure and molecular phylogeography of Sebastiscus marmoratus, "Marine Science" Opening Project of Top Priority from Zhejiang Ocean University, ¥40,000, Project principal.
5) 2019-2021, The mechanism study of breast cancer invasion and metastasis regulated by interaction between EYA2 and PAX6, the National Natural Science Foundation of China for Young Scientists, ¥210,000, principal participant.
6) 2019-2020, Research and development of new carbon-based hemostatic materials, Innovation and International Cooperation Project from Shandong Academy of Sciences, ¥1,200,000, principal participant.
7) 2019, Development and Application of Drug screening Technology System based on Zebrafish Epilepsy Model, Shandong Province High-ranking Foreign Experts Project, ¥217,500, principal participant.
8) 2011-2013, Study on the population genetics of Dasyatis akajei in China, the National Natural Science Foundation of China for Young Scientists, ¥269,800, principal participant.
9) 2013-2016, Research on Germplasm Resources Mining and Selection of Improved Varieties of Culter alburnus, Agricultural Biological Resources Innovation and Utilization Project in Shandong Province, ¥1,000,000, principal participant.
10) 2016-2018, Screening of Gene Mutants Regulating the Formation of Bacillus Spore and Study on Fermentation Technology of Alkaline Protease, the Key Research and Development Project of Shandong Province, ¥100,000, principal participant.
Publications
1) Li N, Chen X, Sun DR, Song N, Lin Q, Gao TX. Phylogeography and population structure of the red stingray, Dasyatis akajei inferred by mitochondrial control region. Mitochondrial DNA, 2015, 26(4): 505-513.
2) Li N, Song N, Gao TX. The complete mitochondrial genome of Japanese Ammodytes personatus (Perciformes, Ammodytidae). Mitochondrial DNA, 2015, 26(5): 781-782.
3) Li N, Zhang ZH, Zhao LL, Gao TX. Complete mitochondrial DNA sequence of the Pacific sand lance Ammodytes hexapterus (Perciformes: Ammodytidae): Mitogenomic perspective on the distinction of Ammodytes hexapterus and Ammodytes personatus. Mitochondrial DNA, 2013, 24: 463-465.
4) Li N, Song N, Cheng GP, Gao TX. Genetic diversity and population structure of the red stingray, Dasyatis akajei inferred by AFLP marker. Biochemical Systematics and Ecology, 2013, 51: 130-137.
5) Gao TX, Li N（共一）, Zhang YP, Shi P. The complete mitochondrial genome of Japanese sandeel Ammodytes personatus (Perciformes, Ammodytidae): Rare structure in control region compared. Mitochondrial DNA, 2013, 24: 320-322.
6) Li X, Dang J, Li Y, Wang LZ, Li N, Liu KC, Jin M. Developmental neurotoxicity fingerprint of silica nanoparticles at environmentally relevant level on larval zebrafish using a neurobehavioral-phenomics-based biological warning method. Science of the Total Environment, https://doi.org/10.1016/j.scitotenv.2020.141878.
7) Li X, Zhang BY, Li N, Ji XN, Liu KC, Jin M. Zebrafish neurobehavioral phenomics applied as the behavioral warning methods for fingerprinting endocrine disrupting effect by lead exposure at environmentally relevant level. Chemosphere, 2019, 231: 315-325.
8) Zhang J, Li N, Zhang ZF, Liu T. Structure analysis of the complete mitochondrial genome in cultivation variety ‘Rongfu’. Journal of Ocean University of China, 2011, 10(4): 351-356.
9) Liu KC, Gao Y, Zhang Y, He QX, Han LW, Li N, Ji XN, Sun C. Zebrafish as a model organism for hearing research. Shandong Science, 2019, 32(5): 46-53 (in Chinese with English Abstract).
10) Sun C, He QX, Gao Y, Zhang L, Li N, Liu KC. Exploring preventive measures for COVID-19 based on the existing virus vaccines. Shandong Science, 2020, 33(2), DOI:10.3976/j.issn.1002-4026.2020.02.001.
Patents
Yang L, Fu PS, Meng QL, Wang XR, Zhang ZS, Li N, Zhu SR, Liu YQ, Zheng HL. A compound microecologics preparation and the ecological cultivation of carp with the preparation (CN 106472368 B)
Awards and other activities
Marine and Fishery Science and Technology of Shandong Province Award (the first prize and the second prize.)
